An exploration of the history, shamanic use, psychoactive effects, current scientific studies, and therapeutic potential of ayahuasca • Examines how ayahuasca affects the brain from a neuroscientific perspective and how its effects on consciousness relate to ancient esoteric texts • Shares interviews with people who have experienced ayahuasca’s powerful “spirit doctor” effects and the author’s own ayahuasca journey from suicidal depression to a soul at peace • Investigates how ayahuasca is interwoven with the ancient practices of Amazonian shamanism Brewed from a combination of two plants--the leaves of Psychotria viridis and the vine stalks of Banisteriopsis caapi--ayahuasca has been used for millennia by indigenous tribes throughout the Upper Amazon for healing and spiritual exploration. The shamans of the Peruvian Amazon call the plant spirit within the vine Abuela Ayahuasca, Grandmother Ayahuasca. Exploring the history, lore, traditional use, psychoactive effects, and current