Reflecting a decade of tremendous growth in mindfulness research and interventions, this authoritative handbook is now in a significantly revised second edition with 75% new material. The volume examines the interface of contemporary psychological science and ancient contemplative traditions. It presents cutting-edge work on the neurobiological, cognitive, emotional, and interpersonal mechanisms and effects of meditative practices. Chapters on exemplary applications review mindfulness-based interventions for both clinical and nonclinical populations. Contributors describe the development of and evidence base for each approach and identify important directions for future investigation.New to This EditionMost chapters are new or extensively updated. Chapters on emotion regulation processes and interventions for chronic pain. Chapters on interventions in school and work settings. Chapter on adapting mindfulness-based research and interventions for Black communities. Chapters on neurophenomenology, process-based research, and Buddhist philosophy.