After its publication in 1967, The Foundations of Scientific Inference taught a generation of students and researchers about the problem of induction, the interpretation of probability, and confirmation theory. Fifty years later, Wesley C. Salmon’s book remains one of the clearest introductions to these fundamental problems in the philosophy of science. This anniversary edition of Salmon’s foundational work features a detailed introduction by Christopher Hitchcock, which examines the book’s origins, influences, and major themes, its impact and enduring effects, the disputes it raised, and its place in current studies, revisiting Salmon’s ideas for a new audience of philosophers, historians, scientists, and students.