Prisbevakning
Få notis vid prissänkningAv: Melinda Mills, Nicola Barban, Felix C. Tropf
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"This book is truly unique in that it is the first comprehensive book that not only provides an introduction to the foundations of human genetics, but also includes a statistical primer, theoretical models and hands-on computer applications. There are many excellent introductory books on human genetics or statistical population genetics, yet most of them are written for advanced graduate and PhD students in biology or genetics. This is in stark contrast with how genetic data is being used in research today, which is increasingly across multiple scientific and research domains. Current textbooks are generally separated into distinct topics. Many focus solely on an introduction to molecular genetics and human evolution. Others provide in-depth treatments of statistical models in this area of research or bioinformatics. Few (if any) provide hands-on computer exercises. To our knowledge there is currently no comparable book on the market that spans and actively links all of these topics. Yet it is precisely these combined and interdisciplinary skills that are now required. Another unique aspect of this book is that it is written at an accessible and introductory level to reach people from a variety of backgrounds. This book is for current and aspiring students and researchers from any empirically oriented medical, biological, behavioural or social science discipline who would like to understand the main concepts of human statistical genetic data analysis, but also practitioners looking for solutions to enter and undertake this research. It is an introductory book, written for those who do not have a strong background in molecular biology, human genetics or statistical genetics, but would like to integrate genetic data into their research. We also made a concerted effort to focus on the basic terminology and practical aspects of statistical genetic data analysis rather than the math, statistics and biology behind it. The book is divided into three interdependent parts. Part I provides the foundations including: (1) fundamental concepts and the human genome, (2) a statistical primer, (3) a primer in human evolution, (4) Genome-Wide Association Studies (GWAS), (5) polygenic scores and genetic architecture; and, (6) gene-environment interplay. Part II delves into the practicalities of how to work with genetic data including: (7) genetic data and challenges, (8) data management I: descriptive statistics, quality control, (9) data management II: association analysis, population stratification and genetic relatedness; and, (10) creating and validating polygenic scores. Part III covers applications and advanced topics, namely: (11) polygenic score and gene-environment interaction applications, (12) applying GWAS results, (13) Mendelian Randomization and instrumental variables, (14) ethical issues; and, (15) conclusions and future directions. We also included two appendices which comprise of: Appendix 1: Software used in this book, Appendix 2: Data used in the book and a brief Glossary"--
Avvakta – priset är högt
Adlibris
Som normalt
Varierar något
Författare
Melinda Mills, Nicola Barban, Felix C. Tropf
Författare
Melinda Mills, Nicola Barban, Felix C. Tropf
Förlag
The MIT Press
Utgivningsår
2020
Sidantal
415
Språk
Engelska
Dewey
572.8/60727
ISBN
9780262538381
Av: Melinda Mills, Nicola Barban, Felix C. Tropf
Lägsta pris
Vi har hittat boken hos 2 butiker med verifierade priser — alla är partnerbutiker som vi får provision från när du klickar på ”Visa hos butik”. Vissa butiker visas som extern länk utan pris — priset ser du först hos butiken. Priset för dig är detsamma. Frakt kan tillkomma och varierar mellan butiker och leveranssätt — kontrollera alltid aktuellt pris och leveransvillkor hos butiken innan du slutför köpet.
Skriver du om boken på en blogg eller sajt? .
Priset har nyligen gått ner jämfört med butikens eget tidigare pris.
Det lägsta priset vi sett för boken sedan Booki började mäta.
Billigaste butiken ligger under de övriga butikernas medianpris just nu — en jämförelse mellan butiker, inte ett prisfall över tid.
Butiken med lägst pris i prislistan på boksidan just nu.
"This book is truly unique in that it is the first comprehensive book that not only provides an introduction to the foundations of human genetics, but also includes a statistical primer, theoretical models and hands-on computer applications. There are many excellent introductory books on human genetics or statistical population genetics, yet most of them are written for advanced graduate and PhD students in biology or genetics. This is in stark contrast with how genetic data is being used in research today, which is increasingly across multiple scientific and research domains. Current textbooks are generally separated into distinct topics. Many focus solely on an introduction to molecular genetics and human evolution. Others provide in-depth treatments of statistical models in this area of research or bioinformatics. Few (if any) provide hands-on computer exercises. To our knowledge there is currently no comparable book on the market that spans and actively links all of these topics. Yet it is precisely these combined and interdisciplinary skills that are now required. Another unique aspect of this book is that it is written at an accessible and introductory level to reach people from a variety of backgrounds. This book is for current and aspiring students and researchers from any empirically oriented medical, biological, behavioural or social science discipline who would like to understand the main concepts of human statistical genetic data analysis, but also practitioners looking for solutions to enter and undertake this research. It is an introductory book, written for those who do not have a strong background in molecular biology, human genetics or statistical genetics, but would like to integrate genetic data into their research. We also made a concerted effort to focus on the basic terminology and practical aspects of statistical genetic data analysis rather than the math, statistics and biology behind it. The book is divided into three interdependent parts. Part I provides the foundations including: (1) fundamental concepts and the human genome, (2) a statistical primer, (3) a primer in human evolution, (4) Genome-Wide Association Studies (GWAS), (5) polygenic scores and genetic architecture; and, (6) gene-environment interplay. Part II delves into the practicalities of how to work with genetic data including: (7) genetic data and challenges, (8) data management I: descriptive statistics, quality control, (9) data management II: association analysis, population stratification and genetic relatedness; and, (10) creating and validating polygenic scores. Part III covers applications and advanced topics, namely: (11) polygenic score and gene-environment interaction applications, (12) applying GWAS results, (13) Mendelian Randomization and instrumental variables, (14) ethical issues; and, (15) conclusions and future directions. We also included two appendices which comprise of: Appendix 1: Software used in this book, Appendix 2: Data used in the book and a brief Glossary"--
Avvakta – priset är högt
Adlibris
Som normalt
Varierar något
Författare
Melinda Mills, Nicola Barban, Felix C. Tropf
Författare
Melinda Mills, Nicola Barban, Felix C. Tropf
Förlag
The MIT Press
Utgivningsår
2020
Sidantal
415
Språk
Engelska
Dewey
572.8/60727
ISBN
9780262538381
2020 · Engelska
Melinda Mills, Nicola Barban, Felix C. Tropf
ISBN 9780262538381 jämförs hos alla butiker
"This book is truly unique in that it is the first comprehensive book that not only provides an introduction to the foundations of human genetics, but also includes a statistical primer, theoretical models and hands-on computer applications. There are many excellent introductory books on human genetics or statistical population genetics, yet most of them are written for advanced graduate and PhD students in biology or genetics. This is in stark contrast with how genetic data is being used in research today, which is increasingly across multiple scientific and research domains. Current textbooks are generally separated into distinct topics. Many focus solely on an introduction to molecular genetics and human evolution. Others provide in-depth treatments of statistical models in this area of research or bioinformatics. Few (if any) provide hands-on computer exercises. To our knowledge there is currently no comparable book on the market that spans and actively links all of these topics. Yet it is precisely these combined and interdisciplinary skills that are now required. Another unique aspect of this book is that it is written at an accessible and introductory level to reach people from a variety of backgrounds. This book is for current and aspiring students and researchers from any empirically oriented medical, biological, behavioural or social science discipline who would like to understand the main concepts of human statistical genetic data analysis, but also practitioners looking for solutions to enter and undertake this research. It is an introductory book, written for those who do not have a strong background in molecular biology, human genetics or statistical genetics, but would like to integrate genetic data into their research. We also made a concerted effort to focus on the basic terminology and practical aspects of statistical genetic data analysis rather than the math, statistics and biology behind it. The book is divided into three interdependent parts. Part I provides the foundations including: (1) fundamental concepts and the human genome, (2) a statistical primer, (3) a primer in human evolution, (4) Genome-Wide Association Studies (GWAS), (5) polygenic scores and genetic architecture; and, (6) gene-environment interplay. Part II delves into the practicalities of how to work with genetic data including: (7) genetic data and challenges, (8) data management I: descriptive statistics, quality control, (9) data management II: association analysis, population stratification and genetic relatedness; and, (10) creating and validating polygenic scores. Part III covers applications and advanced topics, namely: (11) polygenic score and gene-environment interaction applications, (12) applying GWAS results, (13) Mendelian Randomization and instrumental variables, (14) ethical issues; and, (15) conclusions and future directions. We also included two appendices which comprise of: Appendix 1: Software used in this book, Appendix 2: Data used in the book and a brief Glossary"--
Avvakta – priset är högt
Adlibris
Som normalt
Varierar något
Författare
Melinda Mills, Nicola Barban, Felix C. Tropf
Förlag
The MIT Press
Utgivningsår
2020
Sidantal
415
Språk
Engelska
ISBN
9780262538381
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